Helping scientists investigate the unanswered
We will consider providing financial support and/or product supply for novel research proposals that answer important scientific and medical questions in our areas of interest. Grant recipients have the right to publish the results of the study and maintain full control over the research project objectives, design, conduct, data analysis, and interpretation.
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Areas of interest
Amikacin Liposome Inhalation Suspension and Pulmonary Infections
Interventional Amikacin Liposome Inhalation Suspension in Nontuberculous Mycobacterial (NTM) Lung Disease
- NTM in different populations
- By disease severity (e.g., using a severity index)
- Transplant population – pre- and post-transplant
- Cavitary disease
- Retreatment – focus on new courses of treatment
- Assessment of disease
- Biomarkers and genetic markers for NTM diagnosis, comorbidities, and disease progression
- Adverse event management/medication adherence
- Novel antimicrobial combinations with Arikayce in NTM lung disease
- Evaluation of factors affecting patient initiation and acceptance of NTM treatment
Burden of Illness of NTM Lung Disease
- Barriers to appropriate and timely screening of NTM Lung Disease
- Barriers to appropriate guideline-based treatment initiation and treatment adherence with treatment for NTM Lung Disease
- Understand patient reported burden of disease and unmet need for new treatment
Bronchiectasis and Other Neutrophil-Related Disorders
Disease State/Mechanism of Disease
- Epidemiology, natural history, clinical course, and progression of bronchiectasis
- Neutrophil serine protease (NSP) biomarkers of disease severity/burden in patients with autoimmune or inflammatory diseases
- Pre-clinical models of neutrophilic inflammation including the effect of DPP1 inhibition on outcomes and potential new biomarkers primarily with a focus on bronchiectasis
